The notch pathway promotes NF-κB activation through Asb2 in T cell acute lymphoblastic leukemia cells

Abstract Background Oncogenic Notch1 is known to activate the NF-κB pathway in T cell acute lymphoblastic leukemia (T-ALL) and to up-regulate the transcription of Asb2α, a specificity factor for an E3 ubiquitin ligase complex that plays an important role in hematopoietic differentiation. Therefore,...

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Үндсэн зохиолчид:	Wei Wu, Li Nie, Li Zhang, Yan Li
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMC 2018-08-01
Цуврал:	Cellular & Molecular Biology Letters
Нөхцлүүд:	Notch1 NF-κB Asb2 T cell acute lymphoblastic leukemia
Онлайн хандалт:	http://link.springer.com/article/10.1186/s11658-018-0102-4
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!