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Notch and NF-κB: Coach and Players of Regulatory T-Cell Response in Cancer

The Notch signaling pathway plays multiple roles in driving T-cell fate decisions, proliferation, and aberrant growth. NF-κB is a cell-context key player interconnected with Notch signaling either in physiological or in pathological conditions. This review focuses on how the multilayered crosstalk b...

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Hauptverfasser: Francesca Ferrandino, Paola Grazioli, Diana Bellavia, Antonio Francesco Campese, Isabella Screpanti, Maria Pia Felli
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018-10-01
Schriftenreihe:Frontiers in Immunology
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Online-Zugang:https://www.frontiersin.org/article/10.3389/fimmu.2018.02165/full
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