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RAPID, SENSITIVE, NEW AND SIMPLE UPLC-MS/MS VALIDATED METHOD WITH CHARGED SURFACE HYBRID COLUMN FOR DETERMINATION OF ANTI DEPRESSION DRUG SERTRALINE IN HUMAN PLASMA AND ITS APPLICATION TO BIOEQUIVALENCE STUDY

Background: A rapid, simple, sensitive, reproducible, and RP-UPLC-MS/MS method was established and bioanalytically validated for determining Anti depression drug sertraline in human plasma.Methods: Sertraline was extracted from human plasma by protein precipitation technique using cooled acetonitril...

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Autors principals: Yasser Elshayep, waheed Salem, Abdelhameed Ismail, Fathy Abd allah
Format: Artigo
Idioma:Inglês
Publicat: Assiut University, Faculty of Pharmacy 2025-12-01
Col·lecció:Bulletin of Pharmaceutical Sciences. Assiut University
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Accés en línia:https://bpsa.journals.ekb.eg/article_449717_36a0329a538c845f7c3e1e50a1e8b94b.pdf
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