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CXCR5 and TIM-3 expressions define distinct exhausted T cell subsets in experimental cutaneous infection with Leishmania mexicana

T-cell exhaustion is a key stage in chronic infections since it limits immunopathology, but also hinders the elimination of pathogens. Exhausted T (Tex) cells encompass dynamic subsets, including progenitor cells that sustain long-term immunity through their memory/stem like properties, and terminal...

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Збережено в:
Бібліографічні деталі
Автори: Mariana Diupotex, Jaime Zamora-Chimal, Julián A. Gajón, Laura C. Bonifaz, Ingeborg Becker
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2023-08-01
Серія:Frontiers in Immunology
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Онлайн доступ:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1231836/full
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