CXCR5+TIM-3-PD-1+ stem-like cytotoxic CD8+ T cells: elevated in chronic rhinosinusitis and associated with disease severity

BackgroundChronic rhinosinusitis (CRS) is a chronic inflammatory disease with an autoimmune background. Altered expression levels of T cell immunoglobulin and mucin-domain containing-3 (TIM-3), C-X-C chemokine receptor type 5 (CXCR5), and programmed cell death protein 1 (PD-1) are implicated in the...

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Auteurs principaux:	Zhichen Liu, Zixuan Zhao, Huanxia Xie, Ning Lu, Jisheng Liu, Qingqing Jiao
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2024-02-01
Collection:	Frontiers in Immunology
Sujets:	chronic rhinosinusitis PD-1+ CXCR5+ TIM-3- stem-like CD8+ T cells
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2024.1295309/full
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