SETD7-mediated monomethylation is enriched on soluble Tau in Alzheimer’s disease
Abstract Background Human tauopathies including Alzheimer’s disease (AD) are characterized by alterations in the post-translational modification (PTM) pattern of Tau, which parallel the formation of insoluble Tau aggregates, neuronal dysfunction and degeneration. While PTMs on aggregated Tau have be...
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| Автори: | , , , , , , , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2021-07-01
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| Серія: | Molecular Neurodegeneration |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s13024-021-00468-x |
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