Targeted insertion of conditional expression cassettes into the mouse genome using the modified i-PITT
Abstract Background Transgenic (Tg) mice are widely used in biomedical research, and they are typically generated by injecting transgenic DNA cassettes into pronuclei of one-cell stage zygotes. Such animals often show unreliable expression of the transgenic DNA, one of the major reasons for which is...
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| Principais autores: | , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2024-06-01
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| coleção: | BMC Genomics |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12864-024-10250-0 |
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