Integrin α2 is an early marker for osteoclast differentiation that contributes to key steps in osteoclastogenesis

IntroductionOsteoclasts determine bone tissue turnover. Their increased activity causes osteoporosis, their dysfunction osteopetrosis.Methods and ResultsMurine monocytic ER-Hoxb8 cells differentiate into OCs upon treatment with M-CSF and RANKL and upregulate the collagen-binding integrin α2β1 distin...

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Hlavní autoři:	Katrin Brockhaus, Isabel Hemsen, Saskia-Larissa Jauch-Speer, Stephan Niland, Thomas Vogl, Johannes A. Eble
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2024-08-01
Edice:	Frontiers in Cell and Developmental Biology
Témata:	osteoclast integrin α2β1 CD9 collagen differentiation
On-line přístup:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1448725/full
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