Integrin α2 is an early marker for osteoclast differentiation that contributes to key steps in osteoclastogenesis

IntroductionOsteoclasts determine bone tissue turnover. Their increased activity causes osteoporosis, their dysfunction osteopetrosis.Methods and ResultsMurine monocytic ER-Hoxb8 cells differentiate into OCs upon treatment with M-CSF and RANKL and upregulate the collagen-binding integrin α2β1 distin...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Katrin Brockhaus, Isabel Hemsen, Saskia-Larissa Jauch-Speer, Stephan Niland, Thomas Vogl, Johannes A. Eble
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Frontiers Media S.A. 2024-08-01
Schriftenreihe:	Frontiers in Cell and Developmental Biology
Schlagworte:	osteoclast integrin α2β1 CD9 collagen differentiation
Online-Zugang:	https://www.frontiersin.org/articles/10.3389/fcell.2024.1448725/full
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!