Sporadic Parkinson’s disease derived neuronal cells show disease-specific mRNA and small RNA signatures with abundant deregulation of piRNAs

Abstract Differentiated neurons established via iPSCs from patients that suffer from familial Parkinson’s disease (PD) have allowed insights into the mechanisms of neurodegeneration. In the larger cohort of patients with sporadic PD, iPSC based information on disease specific cellular phenotypes is...

पूर्ण विवरण

ग्रंथसूची विवरण

मुख्य लेखकों:	Markus Schulze, Annika Sommer, Sonja Plötz, Michaela Farrell, Beate Winner, Janina Grosch, Jürgen Winkler, Markus J. Riemenschneider
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	BMC 2018-07-01
श्रृंखला:	Acta Neuropathologica Communications
विषय:	Methylation PD Induced pluripotent stem cells iPSC SINE LINE
ऑनलाइन पहुंच:	http://link.springer.com/article/10.1186/s40478-018-0561-x
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