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Sporadic Parkinson’s disease derived neuronal cells show disease-specific mRNA and small RNA signatures with abundant deregulation of piRNAs

Abstract Differentiated neurons established via iPSCs from patients that suffer from familial Parkinson’s disease (PD) have allowed insights into the mechanisms of neurodegeneration. In the larger cohort of patients with sporadic PD, iPSC based information on disease specific cellular phenotypes is...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Markus Schulze, Annika Sommer, Sonja Plötz, Michaela Farrell, Beate Winner, Janina Grosch, Jürgen Winkler, Markus J. Riemenschneider
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMC 2018-07-01
Saila:Acta Neuropathologica Communications
Gaiak:
Sarrera elektronikoa:http://link.springer.com/article/10.1186/s40478-018-0561-x
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