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Future Perspective for ALK-Positive Anaplastic Large Cell Lymphoma with Initial Central Nervous System (CNS) Involvement: Could Next-Generation ALK Inhibitors Replace Brain Radiotherapy for the Prevention of Further CNS Relapse?

Central nervous system (CNS) involvement in anaplastic large cell lymphoma (ALCL) at diagnosis is rare and leads to poor prognosis with the use of the standard ALCL99 protocol alone. CNS-directed intensive chemotherapy, such as an increased dose of intravenous MTX, increased dose of dexamethasone, i...

Deskribapen osoa

Gorde:
Egile Nagusiak: Makito Tanaka, Hiroki Miura, Soichiro Ishimaru, Gen Furukawa, Yoshiki Kawamura, Kei Kozawa, Seiji Yamada, Fumitaka Ito, Kazuko Kudo, Tetsushi Yoshikawa
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2023-05-01
Saila:Pediatric Reports
Gaiak:
anaplastic large cell lymphoma
central nervous system
ALK inhibitor
alectinib
irradiation
children
Sarrera elektronikoa:https://www.mdpi.com/2036-7503/15/2/29
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