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Future Perspective for ALK-Positive Anaplastic Large Cell Lymphoma with Initial Central Nervous System (CNS) Involvement: Could Next-Generation ALK Inhibitors Replace Brain Radiotherapy for the Prevention of Further CNS Relapse?

Central nervous system (CNS) involvement in anaplastic large cell lymphoma (ALCL) at diagnosis is rare and leads to poor prognosis with the use of the standard ALCL99 protocol alone. CNS-directed intensive chemotherapy, such as an increased dose of intravenous MTX, increased dose of dexamethasone, i...

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Uloženo v:
Hlavní autoři: Makito Tanaka, Hiroki Miura, Soichiro Ishimaru, Gen Furukawa, Yoshiki Kawamura, Kei Kozawa, Seiji Yamada, Fumitaka Ito, Kazuko Kudo, Tetsushi Yoshikawa
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2023-05-01
Edice:Pediatric Reports
Témata:
anaplastic large cell lymphoma
central nervous system
ALK inhibitor
alectinib
irradiation
children
On-line přístup:https://www.mdpi.com/2036-7503/15/2/29
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