Successful fresh formulation CD19 CAR-T cell therapy for GAD65 antibody-mediated cerebellar ataxia. A Case Report

BackgroundChimeric antigen receptor T (CAR-T) cell therapy is an effective treatment for treatment-refractory hematological disorders with an acceptable safety profile. In contrast, preliminary reports suggest good efficacy for treatment-refractory autoimmune disorders, including autoimmune nervous...

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Auteurs principaux:	Mantas Vaisvilas, Skirmante Cernauskiene, David Petrosian, Natasa Giedraitiene, Mindaugas Stoskus, Laimonas Griskevicius
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2026-02-01
Collection:	Frontiers in Immunology
Sujets:	autoimmune cerebellar ataxia autoimmune encephalitis CAR-T cell therapy GAD65 antibody gene therapy immunotherapy
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1755797/full
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