Mesenchymal stromal cells for steroid-refractory biopsy-proven grade III-IV acute Graft-versus-Host Disease with predominant gastrointestinal involvement

IntroductionSteroid-refractory acute Graft-versus-Host Disease (SR-aGVHD) is a potentially fatal complication occurring in approximately 60-70% of severe grade III-IV GVHD cases, with a higher incidence in patients with gastrointestinal (GI) involvement. GI aGVHD is associated with poor prognosis, w...

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Principais autores:	Adomas Bukauskas, Renata Jucaitienė, Mindaugas Stoškus, Vilma Valčeckienė, Greta Bušmaitė, Artūras Slobinas, Linas Davainis, Inga Šlepikienė, Igoris Trociukas, Valdas Pečeliūnas, Laimonas Griškevičius, Andrius Žučenka
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2025-05-01
coleção:	Frontiers in Immunology
Assuntos:	acute Graft-versus-Host Disease (aGVHD) steroid-refractory acute Graft-versus-Host Disease (SR-aGVHD) bone marrow-derived MSC (BM-MSC) grade III-IV SR aGVHD gastrointestinal GVHD mesenchymal stromal cells (MSC)
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1600019/full
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