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Changes in Rosuvastatin Pharmacokinetics During Postnatal Ontogenesis in Rats

Purpose: Statin therapy should be considered in children with familial hypercholesterolemia and sustained high LDL-C levels. There are no data on rosuvastatin exposure in patients <6 years and efficacy/safety can only be derived from case reports. Our aim was to examine developmental changes in phar...

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Bibliografische gegevens
Hoofdauteurs: Jaroslava Roušarová, Martin Šíma, Petr Kozlík, Tomáš Křížek, Ondřej Slanař
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Frontiers Media S.A. 2021-12-01
Reeks:Journal of Pharmacy & Pharmaceutical Sciences
Online toegang:https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/32342
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