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Improved Dissolution and Pharmacokinetics of Abiraterone through KinetiSol<sup>®</sup> Enabled Amorphous Solid Dispersions

Abiraterone is a poorly water-soluble drug. It has a high melting point and limited solubility in organic solvents, making it difficult to formulate as an amorphous solid dispersion (ASD) with conventional technologies. KinetiSol<sup>®</sup> is a high-energy, fusion-based, solvent-free technology th...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Urvi Gala, Dave Miller, Robert O. Williams
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2020-04-01
Schriftenreihe:Pharmaceutics
Schlagworte:
Online-Zugang:https://www.mdpi.com/1999-4923/12/4/357
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