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Induction of endogenous γ-globin gene expression with decoy oligonucleotide targeting Oct-1 transcription factor consensus sequence

<p>Abstract</p> <p>Human β-globin disorders are relatively common genetic diseases cause by mutations in the β-globin gene. Increasing the expression of the <it>γ</it>-globin gene has great benefits in reducing complications associated with these diseases. The Oct-1 transcription factor is involved...

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Autors principals: Wang Gan, Hong Xin, Xu Xiaoxin S
Format: Artigo
Idioma:Inglês
Publicat: BMC 2009-03-01
Col·lecció:Journal of Hematology & Oncology
Accés en línia:http://www.jhoonline.org/content/2/1/15
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