Induction of endogenous γ-globin gene expression with decoy oligonucleotide targeting Oct-1 transcription factor consensus sequence
<p>Abstract</p> <p>Human β-globin disorders are relatively common genetic diseases cause by mutations in the β-globin gene. Increasing the expression of the <it>γ</it>-globin gene has great benefits in reducing complications associated with these diseases. The Oct-1 transcription factor is involved...
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| Автори: | , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2009-03-01
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| Серія: | Journal of Hematology & Oncology |
| Онлайн доступ: | http://www.jhoonline.org/content/2/1/15 |
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