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Effects of Neurogenin 3 Induction on Endocrine Differentiation and Delamination in Adult Human Pancreatic Ductal Organoids

Diabetes mellitus is characterized by the loss of pancreatic insulin-secreting β-cells in the Islets of Langerhans. Understanding the regenerative potential of human islet cells is relevant in the context of putative restoration of islet function after damage and novel islet cell replacement therapi...

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Hlavní autoři: Juri Juksar, Rachel Mijdam, Sabine Bosman, Alexander van Oudenaarden, Françoise Carlotti, Eelco J. P. de Koning
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-04-01
Edice:Transplant International
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On-line přístup:https://www.frontierspartnerships.org/articles/10.3389/ti.2025.13422/full
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