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Effects of Neurogenin 3 Induction on Endocrine Differentiation and Delamination in Adult Human Pancreatic Ductal Organoids

Diabetes mellitus is characterized by the loss of pancreatic insulin-secreting β-cells in the Islets of Langerhans. Understanding the regenerative potential of human islet cells is relevant in the context of putative restoration of islet function after damage and novel islet cell replacement therapi...

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Bibliografiska uppgifter
Huvudupphov: Juri Juksar, Rachel Mijdam, Sabine Bosman, Alexander van Oudenaarden, Françoise Carlotti, Eelco J. P. de Koning
Materialtyp: Artigo
Språk:Inglês
Utgiven: Frontiers Media S.A. 2025-04-01
Serie:Transplant International
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Länkar:https://www.frontierspartnerships.org/articles/10.3389/ti.2025.13422/full
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