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Single-cell transcriptome analysis of NEUROG3+ cells during pancreatic endocrine differentiation with small molecules

Abstract The efficiency of inducing human embryonic stem cells into NEUROG3+ pancreatic endocrine cells is a bottleneck in stem cell therapy for diabetes. To understand the cell properties and fate decisions during differentiation, we analyzed the modified induction method using single-cell transcri...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Jin Li, Junru Chen, Xiaoyu Luo, Guangxiu Lu, Ge Lin
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: BMC 2023-04-01
Цуврал:Stem Cell Research & Therapy
Нөхцлүүд:
Онлайн хандалт:https://doi.org/10.1186/s13287-023-03338-z
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