Targeting the lactylation of ENO1 alleviates endothelial dysfunction in sepsis

Abstract Background Elevated lactate is associated with vascular endothelial dysfunction, a factor that can contribute to organ failure in sepsis. However, the specific mechanisms involved have yet to be fully elucidated. Here, we investigated the role of enolase 1 (ENO1) lactylation in modulating t...

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主要な著者:	Xueru Xie, Tingyan Liu, Caiyan Zhang, Ye Cheng, Yajing Gao, Wenfeng Xiao, Haiyan Guo, Yutong Zhou, Yawei Yu, Kexin Wang, Yinghong Lin, Lisheng Xiao, Yingying Zhang, Weiguo Yang, Gangfeng Yan, Guoping Lu, Yufeng Zhou
フォーマット:	Artigo
言語:	Inglês
出版事項:	Wiley 2026-01-01
シリーズ:	Clinical and Translational Medicine
主題:	endothelial dysfunction ENO1 lactylation sepsis
オンライン･アクセス:	https://doi.org/10.1002/ctm2.70597
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