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Targeting the lactylation of ENO1 alleviates endothelial dysfunction in sepsis

Abstract Background Elevated lactate is associated with vascular endothelial dysfunction, a factor that can contribute to organ failure in sepsis. However, the specific mechanisms involved have yet to be fully elucidated. Here, we investigated the role of enolase 1 (ENO1) lactylation in modulating t...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Xueru Xie, Tingyan Liu, Caiyan Zhang, Ye Cheng, Yajing Gao, Wenfeng Xiao, Haiyan Guo, Yutong Zhou, Yawei Yu, Kexin Wang, Yinghong Lin, Lisheng Xiao, Yingying Zhang, Weiguo Yang, Gangfeng Yan, Guoping Lu, Yufeng Zhou
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Wiley 2026-01-01
Cyfres:Clinical and Translational Medicine
Pynciau:
Mynediad Ar-lein:https://doi.org/10.1002/ctm2.70597
Tagiau: Ychwanegu Tag
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