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Natural Sesquiterpene Lactones of the 4,15-<i>iso</i>-Atriplicolide Type are Inhibitors of Trypanothione Reductase

In the course of our investigations on the antitrypanosomal potential of sesquiterpene lactones (STL), we have recently reported on the exceptionally strong activity of 4,15-<i>iso</i>-Atriplicolide tiglate, which demonstrated an IC<sub>50</sub> value of 15 nM against <i>Trypanosoma brucei rhodesien...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Mairin Lenz, R. Luise Krauth-Siegel, Thomas J. Schmidt
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2019-10-01
Rangatū:Molecules
Ngā marau:
Urunga tuihono:https://www.mdpi.com/1420-3049/24/20/3737
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