Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic Reticulum

The most common cystic fibrosis-causing mutation (F508del, present in ~85% of CF patients) leads to CFTR misfolding, which is recognized by the endoplasmic reticulum (ER) quality control (ERQC), resulting in ER retention and early degradation. It is known that CFTR exit from the ER is mediated by sp...

Deskribapen osoa

Xehetasun bibliografikoak

Egile Nagusiak:	João D. Santos, Sara Canato, Ana S. Carvalho, Hugo M. Botelho, Kerman Aloria, Margarida D. Amaral, Rune Matthiesen, Andre O. Falcao, Carlos M. Farinha
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	MDPI AG 2019-04-01
Saila:	Cells
Gaiak:	CFTR endoplasmic reticulum quality control arginine-framed tripeptides diacidic code interactome folding trafficking
Sarrera elektronikoa:	https://www.mdpi.com/2073-4409/8/4/353
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!