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CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity

Natural Killer (NK) cells are innate immune cells that can directly detect and kill cancer cells. Understanding the molecular determinants regulating human NK cell cytotoxicity could help harness these cells for cancer therapies. To this end, we compared the transcriptome of NK cell clones derived f...

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Hlavní autoři: Camille Rey, Katherine L. Jones, Kevin B. Stacey, Alicia Evans, Jonathan D. Worboys, Gareth Howell, Sam Sheppard, Daniel M. Davis
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-02-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1526379/full
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