CD8α and CD70 mark human natural killer cell populations which differ in cytotoxicity

Natural Killer (NK) cells are innate immune cells that can directly detect and kill cancer cells. Understanding the molecular determinants regulating human NK cell cytotoxicity could help harness these cells for cancer therapies. To this end, we compared the transcriptome of NK cell clones derived f...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Camille Rey, Katherine L. Jones, Kevin B. Stacey, Alicia Evans, Jonathan D. Worboys, Gareth Howell, Sam Sheppard, Daniel M. Davis
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2025-02-01
Цуврал:	Frontiers in Immunology
Нөхцлүүд:	NK cells CD8 CD70 cytotoxicity RNA sequencing cancer immunotherapy
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fimmu.2025.1526379/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!