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Optimizing T cell transduction: a novel transduction device for efficient and scalable gene delivery

Abstract Background Viral transduction is a critical step in the manufacturing of genetically modified T cells for immunotherapies, yet conventional transduction methods suffer from low to medium efficiency, high vector consumption, and limited scalability. Methods To address these challenges, we in...

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Huvudupphov: Kang-Zheng Lee, Tan Dai Nguyen, Dan Liu
Materialtyp: Artigo
Språk:Inglês
Utgiven: BMC 2025-08-01
Serie:Journal of Translational Medicine
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Länkar:https://doi.org/10.1186/s12967-025-06836-1
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