Identification of a small molecule for enhancing lentiviral transduction of T cells

Genetic modification of cells using viral vectors has shown huge therapeutic benefit in multiple diseases. However, inefficient transduction contributes to the high cost of these therapies. Several transduction-enhancing small molecules have previously been identified; however, some may be toxic to...

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מידע ביבליוגרפי

Principais autores:	Paulina Malach, Charlotte Kay, Chris Tinworth, Florence Patel, Bryan Joosse, Jennifer Wade, Marlene Rosa do Carmo, Brian Donovan, Martijn Brugman, Claudia Montiel-Equihua, Natalie Francis
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Elsevier 2023-12-01
סדרה:	Molecular Therapy: Methods & Clinical Development
נושאים:	transduction enhancer lentivirus lentiviral transduction T cell T cell therapy cancer immunotherapy
גישה מקוונת:	http://www.sciencedirect.com/science/article/pii/S2329050123001523
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!