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Identification of a small molecule for enhancing lentiviral transduction of T cells

Genetic modification of cells using viral vectors has shown huge therapeutic benefit in multiple diseases. However, inefficient transduction contributes to the high cost of these therapies. Several transduction-enhancing small molecules have previously been identified; however, some may be toxic to...

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Bibliografiske detaljer
Principais autores: Paulina Malach, Charlotte Kay, Chris Tinworth, Florence Patel, Bryan Joosse, Jennifer Wade, Marlene Rosa do Carmo, Brian Donovan, Martijn Brugman, Claudia Montiel-Equihua, Natalie Francis
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2023-12-01
Serier:Molecular Therapy: Methods & Clinical Development
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Online adgang:http://www.sciencedirect.com/science/article/pii/S2329050123001523
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