Combined effects of restriction factors and transduction adjuvants on lentiviral vector gene transfer efficacy

Abstract Restriction factors include various cellular proteins that detect and impede viral infections. Among them, interferon-induced transmembrane (IFITM) and serine incorporator (SERINC) proteins interfere with the infectious cycle of HIV-1. Consequently, such restriction factors can also interfe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Marie Dewannieux, Fatoumata Fofana, Kathleen Hamon, Mirella Mormin, Anne Galy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Portfolio 2025-11-01
Saila:Scientific Reports
Gaiak:
Lentiviral vector
Gene therapy
Restriction factor
Viral transduction
Sarrera elektronikoa:https://doi.org/10.1038/s41598-025-22470-9
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