Combined effects of restriction factors and transduction adjuvants on lentiviral vector gene transfer efficacy

Abstract Restriction factors include various cellular proteins that detect and impede viral infections. Among them, interferon-induced transmembrane (IFITM) and serine incorporator (SERINC) proteins interfere with the infectious cycle of HIV-1. Consequently, such restriction factors can also interfe...

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Bibliografski detalji

Glavni autori:	Marie Dewannieux, Fatoumata Fofana, Kathleen Hamon, Mirella Mormin, Anne Galy
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2025-11-01
Serija:	Scientific Reports
Teme:	Lentiviral vector Gene therapy Restriction factor Viral transduction
Online pristup:	https://doi.org/10.1038/s41598-025-22470-9
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