USP13 regulates HMGB1 stability and secretion through its deubiquitinase activity
Abstract Background High mobility group box 1 (HMGB1) is a damage-associated molecular pattern (DAMP) molecule that plays a central role in innate immunity. HMGB1 acts as a late mediator of inflammation when actively secreted in response to inflammatory stimuli. Several post-translational modificati...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BMC
2022-12-01
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| Seria: | Molecular Medicine |
| Hasła przedmiotowe: | |
| Dostęp online: | https://doi.org/10.1186/s10020-022-00596-0 |
| Etykiety: |
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