[¹²⁵I]IPC-Lecanemab: Synthesis and Evaluation of Aβ-Plaque-Binding Antibody and Comparison with Small-Molecule [¹⁸F]Flotaza and [¹²⁵I]IBETA in Postmortem Human Alzheimer’s Disease

Therapeutic antibodies for reducing Aβ plaque load in Alzheimer’s disease (AD) is currently making rapid progress. The diagnostic imaging of Aβ plaque load in AD has been underway and is now used in clinical studies. Here, we report our preliminary findings on imaging a therapeutic antibody, Lecanem...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Christopher Liang, Cayz G. Paclibar, Noresa L. Gonzaga, Stephanie A. Sison, Harman S. Bath, Agnes P. Biju, Jogeshwar Mukherjee
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	MDPI AG 2024-04-01
سلاسل:	Neurology International
الموضوعات:	Lecanemab Aducanumab iodine-125 human postmortem AD PET autoradiography
الوصول للمادة أونلاين:	https://www.mdpi.com/2035-8377/16/2/31
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!