Código QR (código de barras bidimensional)

Towards Imaging Tau Hyperphosphorylation: Is DYRK1A a Potential Target for Imaging Hyperphosphorylation of Tau? Molecular Modeling Assessment and Synthesis of [<sup>125</sup>I]Radioiodinated DYRK1A Inhibitor

Dual specificity tyrosine-phosphorylation regulated kinase 1A (DYRK1A), a phosphorylation kinase, is localized within the central nervous system and is linked to hyperphosphorylation of Tau. Imaging of DYRK1A may provide an earlier biomarker for Tauopathies, including Alzheimer’s disease (AD). We ha...

תיאור מלא

שמור ב:
Principais autores: Cayz G. Paclibar, Deanna M. Schafer, Agnes P. Biju, Fariha Karim, Stephanie A. Sison, Christopher Liang, Shamiha T. Ahmed, Jogeshwar Mukherjee
פורמט: Artigo
שפה:Inglês
יצא לאור: MDPI AG 2025-02-01
סדרה:Molecules
נושאים:
[<sup>125</sup>I]IPPI
[<sup>125</sup>I]KuFal184
DYRK1A
post-mortem human Tau
Alzheimer’s disease
down syndrome
גישה מקוונת:https://www.mdpi.com/1420-3049/30/5/990
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים