[¹²⁵I]INFT: Synthesis and Evaluation of a New Imaging Agent for Tau Protein in Post-Mortem Human Alzheimer’s Disease Brain

Aggregation of Tau protein into paired helical filaments causing neurofibrillary tangles (NFT) is a neuropathological feature in Alzheimer’s disease (AD). This study aimed to develop and evaluate the effectiveness of a novel radioiodinated tracer, 4-[¹²⁵I]iodo-3-(1H-pyrrolo[2,3-c]pyridine...

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Principais autores:	Roz R. Limpengco, Christopher Liang, Yasmin K. Sandhu, Jogeshwar Mukherjee
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2023-07-01
Series:	Molecules
Assuntos:	[<sup>125</sup>I]INFT [<sup>125</sup>I]IPPI post-mortem human Tau Alzheimer’s disease neurofibrillary tangles autoradiography
Acceso en liña:	https://www.mdpi.com/1420-3049/28/15/5769
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