Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum

Abstract Background Malaria parasites are genetically polymorphic and phenotypically plastic. In studying transcriptome variation among parasites from different infections, it is challenging to overcome potentially confounding technical and biological variation between samples. We investigate variat...

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Principais autores:	Sarah J. Tarr, Ofelia Díaz-Ingelmo, Lindsay B. Stewart, Suzanne E. Hocking, Lee Murray, Craig W. Duffy, Thomas D. Otto, Lia Chappell, Julian C. Rayner, Gordon A. Awandare, David J. Conway
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2018-12-01
Series:	BMC Genomics
Assuntos:	Eukaryotic microbial genomics Biological replicates Clinical samples Culture adaptation RNA-seq Transcriptomic methods
Acceso en liña:	http://link.springer.com/article/10.1186/s12864-018-5257-x
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