Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum

Abstract Background Malaria parasites are genetically polymorphic and phenotypically plastic. In studying transcriptome variation among parasites from different infections, it is challenging to overcome potentially confounding technical and biological variation between samples. We investigate variat...

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Autors principals:	Sarah J. Tarr, Ofelia Díaz-Ingelmo, Lindsay B. Stewart, Suzanne E. Hocking, Lee Murray, Craig W. Duffy, Thomas D. Otto, Lia Chappell, Julian C. Rayner, Gordon A. Awandare, David J. Conway
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2018-12-01
Col·lecció:	BMC Genomics
Matèries:	Eukaryotic microbial genomics Biological replicates Clinical samples Culture adaptation RNA-seq Transcriptomic methods
Accés en línia:	http://link.springer.com/article/10.1186/s12864-018-5257-x
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