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Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum

Abstract Background Malaria parasites are genetically polymorphic and phenotypically plastic. In studying transcriptome variation among parasites from different infections, it is challenging to overcome potentially confounding technical and biological variation between samples. We investigate variat...

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Principais autores: Sarah J. Tarr, Ofelia Díaz-Ingelmo, Lindsay B. Stewart, Suzanne E. Hocking, Lee Murray, Craig W. Duffy, Thomas D. Otto, Lia Chappell, Julian C. Rayner, Gordon A. Awandare, David J. Conway
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2018-12-01
Serier:BMC Genomics
Fag:
Eukaryotic microbial genomics
Biological replicates
Clinical samples
Culture adaptation
RNA-seq
Transcriptomic methods
Online adgang:http://link.springer.com/article/10.1186/s12864-018-5257-x
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