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Schizont transcriptome variation among clinical isolates and laboratory-adapted clones of the malaria parasite Plasmodium falciparum

Abstract Background Malaria parasites are genetically polymorphic and phenotypically plastic. In studying transcriptome variation among parasites from different infections, it is challenging to overcome potentially confounding technical and biological variation between samples. We investigate variat...

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Збережено в:
Автори: Sarah J. Tarr, Ofelia Díaz-Ingelmo, Lindsay B. Stewart, Suzanne E. Hocking, Lee Murray, Craig W. Duffy, Thomas D. Otto, Lia Chappell, Julian C. Rayner, Gordon A. Awandare, David J. Conway
Формат: Artigo
Мова:Inglês
Опубліковано: BMC 2018-12-01
Серія:BMC Genomics
Предмети:
Eukaryotic microbial genomics
Biological replicates
Clinical samples
Culture adaptation
RNA-seq
Transcriptomic methods
Онлайн доступ:http://link.springer.com/article/10.1186/s12864-018-5257-x
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