Optogenetic engineering of BAX to control mitochondrial permeabilization and attenuate apoptosis in cells
Abstract Although considerable research has focused on enhancing the apoptotic function of BAX for several decades, inhibition of its functionality remains relatively underexplored, despite intensive BAX activation occurring in various neurodegenerative diseases. Here we present a protein engineerin...
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| Auteurs principaux: | , , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2025-12-01
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| Collection: | Experimental and Molecular Medicine |
| Accès en ligne: | https://doi.org/10.1038/s12276-025-01605-y |
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