Optogenetic engineering of BAX to control mitochondrial permeabilization and attenuate apoptosis in cells
Abstract Although considerable research has focused on enhancing the apoptotic function of BAX for several decades, inhibition of its functionality remains relatively underexplored, despite intensive BAX activation occurring in various neurodegenerative diseases. Here we present a protein engineerin...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Nature Publishing Group
2025-12-01
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| Серии: | Experimental and Molecular Medicine |
| Online-ссылка: | https://doi.org/10.1038/s12276-025-01605-y |
| Метки: |
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