Targeted radionuclide therapy against GARP expressing T regulatory cells after tumour priming with external beam radiotherapy in a murine syngeneic model

Purpose: Radiation therapy (RT) exerts its anti-tumour efficacy by inducing direct damage to cancer cells but also through modification of the tumour microenvironment (TME) by inducing immunogenic antitumor response. Conversely, RT also promotes an immunosuppressive TME notably through the recruitme...

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Detalhes bibliográficos

Principais autores:	Pierre-Simon Bellaye, Alexandre MM. Dias, Jean-Marc Vrigneaud, Alexanne Bouchard, Mathieu Moreau, Camille Petitot, Claire Bernhard, Michael Claron, Lisa Froidurot, Véronique Morgand, Mélanie Guillemin, Marie Monterrat, Céline Mirjolet, Carmen Garrido, Evelyne Kohli, Bertrand Collin
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2024-10-01
Colecção:	Heliyon
Assuntos:	GARP Targeted radionuclide therapy T regulatory cells External beam radiotherapy SPECT imaging
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2405844024155740
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