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X-linked Charcot Marie Tooth mutations alter CO2 sensitivity of connexin32 hemichannels

Connexin32 (Cx32) is expressed in myelinating Schwann cells. It forms both reflexive gap junctions, to facilitate transfer of molecules from the outer to the inner myelin layers and hemichannels at the paranode to permit action potential-evoked release of ATP into the extracellular space. Loss of fu...

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Bibliografische Detailangaben
Hauptverfasser: Jack Butler, Nicholas Dale
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2023-12-01
Schriftenreihe:Frontiers in Cellular Neuroscience
Schlagworte:
Online-Zugang:https://www.frontiersin.org/articles/10.3389/fncel.2023.1330983/full
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