Connexin-43 hemichannels orchestrate NOD-like receptor protein-3 (NLRP3) inflammasome activation and sterile inflammation in tubular injury

Abstract Background Without a viable cure, chronic kidney disease is a global health concern. Inflammatory damage in and around the renal tubules dictates disease severity and is contributed to by multiple cell types. Activated in response to danger associated molecular patterns (DAMPs) including AT...

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Autors principals:	Elena Roger, Christos E. Chadjichristos, Panagiotis Kavvadas, Gareth W. Price, Chelsy L. Cliff, Safia Hadjadj, Jessy Renciot, Paul E. Squires, Claire E. Hills
Format:	Artigo
Idioma:	Inglês
Publicat:	BMC 2023-09-01
Col·lecció:	Cell Communication and Signaling
Matèries:	Connexins Connexin 43 Hemichannels Inflammation Inflammasomes Kidney disease
Accés en línia:	https://doi.org/10.1186/s12964-023-01245-7
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