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X-linked Charcot Marie Tooth mutations alter CO2 sensitivity of connexin32 hemichannels

Connexin32 (Cx32) is expressed in myelinating Schwann cells. It forms both reflexive gap junctions, to facilitate transfer of molecules from the outer to the inner myelin layers and hemichannels at the paranode to permit action potential-evoked release of ATP into the extracellular space. Loss of fu...

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Autori principali: Jack Butler, Nicholas Dale
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2023-12-01
Serie:Frontiers in Cellular Neuroscience
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Accesso online:https://www.frontiersin.org/articles/10.3389/fncel.2023.1330983/full
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