Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena.
The intra-S phase checkpoint kinase of metazoa and yeast, ATR/MEC1, protects chromosomes from DNA damage and replication stress by phosphorylating subunits of the replicative helicase, MCM2-7. Here we describe an unprecedented ATR-dependent pathway in Tetrahymena thermophila in which the essential p...
Kaydedildi:
| Asıl Yazarlar: | , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Public Library of Science (PLoS)
2015-07-01
|
| Seri Bilgileri: | PLoS Genetics |
| Online Erişim: | http://europepmc.org/articles/PMC4517752?pdf=render |
| Etiketler: |
Etiket eklenmemiş, İlk siz ekleyin!
|