QR Code

Checkpoint Activation of an Unconventional DNA Replication Program in Tetrahymena.

The intra-S phase checkpoint kinase of metazoa and yeast, ATR/MEC1, protects chromosomes from DNA damage and replication stress by phosphorylating subunits of the replicative helicase, MCM2-7. Here we describe an unprecedented ATR-dependent pathway in Tetrahymena thermophila in which the essential p...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Pamela Y Sandoval, Po-Hsuen Lee, Xiangzhou Meng, Geoffrey M Kapler
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Public Library of Science (PLoS) 2015-07-01
Rangatū:PLoS Genetics
Urunga tuihono:http://europepmc.org/articles/PMC4517752?pdf=render
Ngā Tūtohu: Tāpirihia he Tūtohu
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!