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PrP(Sc)-specific antibodies with the ability to immunodetect prion oligomers.

The development of antibodies with binding capacity towards soluble oligomeric forms of PrPSc recognised in the aggregation process in early stage of the disease would be of paramount importance in diagnosing prion diseases before extensive neuropathology has ensued. As blood transfusion appears to...

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Autors principals: Mourad Tayebi, Daryl Rhys Jones, William Alexander Taylor, Benjamin Frederick Stileman, Charlotte Chapman, Deming Zhao, Monique David
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science (PLoS) 2011-01-01
Col·lecció:PLoS ONE
Accés en línia:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21625515/?tool=EBI
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